منابع مشابه
Ran
How is Ran involved in nuclear transport? Cargo is transported through pores in the nuclear envelope, in association with carriers that bind to pore proteins called nucleoporins. A Ran–GTP gradient across the envelope is created by the asymmetric distribution of the GTPase activating protein known as RanGAP, which is in the cytosol, and of the guanine nucleotide exchange factor RanGEF in the nu...
متن کاملMicrotubule cytoskeleton: No longer an also Ran
The Ran GTPase cycle has been extensively studied in the context of nuclear transport. Recent work indicates that this GTPase cycle also plays an important role in regulating the microtubule cytoskeleton.
متن کاملSmall GTPase Ran and Ran-binding proteins.
Abstract Like many other small GTPases, Ran functions in eukaryotic cells as a molecular switch that cycles between GTP- and GDP-bound forms. Through the proper modulation of the GTP/GDP cycle, Ran functions with a number of Ran-binding proteins to control a broad array of fundamental cellular functions, including nucleocytoplasmic transport, mitotic spindle assembly, and nuclear envelope and n...
متن کاملThe ran decathlon: multiple roles of Ran.
The Ran GTPase system affects many cellular processes, including the regulation of cell cycle progression, nuclear envelope structure and function, and nucleocytoplasmic transport. The biochemical basis for the involvement of Ran in nuclear import and export has been well documented, but the direct targets of Ran in other cellular processes have not yet been identified. There is, however, mount...
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Antislip-Masterbatche rauen durch nicht aufgeschlossene Partikel die Ober-fläche von Folien auf, um ihnen rutschhemmende Eigenschaften zu verleihen. Die Folie bleibt transluzent; die Stippen sind in diesem Fall gewollt. Die Wirkstoffe haben im Allgemeinen innerhalb der üblichen Dosierung eine Zulassung laut BfR. Die einzelnen Daten sind den Produktinformationsblättern zu entnehmen. Zulassungen ...
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ژورنال
عنوان ژورنال: CME
سال: 2015
ISSN: 1614-371X,1614-3744
DOI: 10.1007/s11298-015-5464-6